Tnion-Plus Capsules

Composition – Each soft gelatin capsule contains:

  • Isotretinoin – USP 20 mg
  • Excipients Q.S.

Approved color used in soft gelatin capsule shells.

Dosage- As directed by the physician.

Keep out of reach of children.

Store in a cool, dry and dark place. Keep away from direct Sunlight.

Description

Here, are some pointers to know about our product Tnion-Plus Capsules.

 Uses of Tnoin Capsules

  1. Severe nodular or cystic acne (main indication)
  2. Acne resistant to antibiotics or topical treatments
  3. Acne with a risk of scarring or psychological distress
  4. Off- label uses (only under specialist supervision):
    • Certain cases of rosacea
    • Seborrhea (excessively oily skin)
    • Hidradenitis suppurativa
    • Folliculitis decalvans (scalp folliculitis)
    • Rare skin cancers (investigational)

Precautions Before and During Use

Isotretinoin is highly effective, but requires strict precautions due to its potential for serious side effects.

 Absolute Contraindications

  • Pregnancy: Extremely teratogenic (causes severe birth defects).
  • Breastfeeding
  • Allergy to isotretinoin or its components

 Precautions

  1. Pregnancy Prevention Program:
    • Negative pregnancy tests before, during, and after treatment
    • Use of two forms of birth control (one hormonal + one barrier method) for females of childbearing potential
    • Avoid pregnancy for 1 month before, during, and 1 month after treatment
  2. Liver Function & Lipids:
    • Monitor liver enzymes and cholesterol/triglycerides before and during treatment (can become elevated)
  3. Mental Health Monitoring:
    • Risk of depression, mood swings, and rarely suicidal thoughts
    • Patients with a history of mental illness should be closely monitored
  4. Avoid Alcohol (increases liver strain and may worsen triglyceride levels)
  5. Avoid Vitamin A Supplements:
    • Increases risk of toxicity (isotretinoin is a vitamin A derivative)
  6. Sun Sensitivity:
    • Use sunscreen and avoid prolonged sun exposure
  7. Avoid Waxing or Dermabrasion:
    • Fragile skin during treatment and for up to 6 months after

 Benefits of Tnoin Capsules

  1. Long-Term Acne Remission:
    • Can provide permanent improvement after a single course in many patients
  2. Reduces Scarring:
    • By treating severe acne early and effectively
  3. Improved Self-Esteem & Quality of Life:
    • Reduces psychological burden of chronic acne
  4. Shrinks Sebaceous Glands:
    • Reduces oil production, clogged pores, and inflammation
  5. Anti-Inflammatory Effects:
    • Helps reduce redness and swelling in severe acne

 Summary Table

Category Details
Main Use Severe, cystic, or treatment-resistant acne
Common Benefits Clear skin, reduced scarring, improved self-image
Major Risks Birth defects, liver/lipid issues, mental health effects
Monitoring Pregnancy tests, liver function tests, lipid profile
Avoid Alcohol, vitamin A, sun exposure, waxing, pregnancy

 

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